Abstract
Inflammatory diseases of the oral cavity, such as stomatitis and gingivitis, are among the most common conditions in dental practice and often require long-term and комплекс treatment approaches. In recent years, increasing attention has been paid to the integration of traditional medicine with modern therapeutic methods. This study aimed to evaluate the clinical effectiveness of the dietary supplement Oregano As, prepared from a 1:1 mixture of Salvia officinalis and Origanum titthanthum, in the management of inflammatory diseases of the oral cavity.The study included 50 patients diagnosed with stomatitis and gingivitis who were divided into a control group (n = 25), receiving conventional dental treatment, and an experimental group (n = 25), receiving standard therapy combined with Oregano AS. Clinical symptoms such as pain, swelling, redness, and bleeding were assessed over a 10-day treatment period.The results demonstrated a significant reduction in inflammatory symptoms in the experimental group, with 95% of patients showing complete clinical improvement compared to 60% in the control group. Symptom relief occurred faster in the experimental group, and enhanced oral mucosal regeneration and improved immune status were observed. These findings indicate that Oregano As exhibits pronounced anti-inflammatory, antiseptic, and regenerative effects and may serve as an effective adjunct to conventional dental therapy.
References
Dzholymbetov, O. N., & Shynybekova, D. (2019). The role of medicinal plants in human life. Theory and Practice of Modern Science, 12(54), 108–110.
2. Khozhimatov, O. K. (2021). Medicinal plants of Uzbekistan: Properties, application and rational use. Tashkent: Ma’naviyat Publishing House.
3. Zimina, L. B., & Konon, N. T. (1999). Biology of flowering of Origanum vulgare L. cultivated in Moscow conditions. Plant Resources, 4, 25–30.
4. Maithani, R., Singh, P., Rawat, S., & Kumar, V. (2023). Botanical description, cultivation practices, essential oil composition and therapeutic values of Origanum vulgare L. and its future prospects. Current Agriculture Research Journal, 11(2), 348–361. https://doi.org/10.12944/CARJ.11.2.18
5. Jumanova, B. G. (2023). Chemical composition of the medicinal plant Salvia officinalis and its use in folk medicine. In Academic Research in Modern Science (Vol. 2, Issue 26, pp. 158–162). Zenodo. https://scholar.google.com/citations?view_op=view_citation&hl=ru&user=5yBnCGoAAAAJ&citation_for_view=5yBnCGoAAAAJ:Se3iqnhoufwC
6. Jumanova, B. G., & Mamatkulova, S. A. (2023). Chemical composition of medicinal sage (Salvia officinalis) and its application in traditional medicine. Journal of Chemistry of Goods and Traditional Medicine. https://scholar.google.com/citations?view_op=view_citation&hl=ru&user=5yBnCGoAAAAJ&citation_for_view=5yBnCGoAAAAJ:roLk4NBRz8UC
7. Jumanova, B. G. (2025). Pharmacological and toxicological properties of the dietary supplement “Oregano-AS”. In Proceedings of the International Educators Conference. https://scholar.google.com/citations?view_op=view_citation&hl=ru&user=5yBnCGoAAAAJ&citation_for_view=5yBnCGoAAAAJ:MXK_kJrjxJIC
8. Jumanova, B. G. (2024). Determination of amino acid content in the dietary supplement “Oregano-AS”. Internauka. https://scholar.google.com/citations?view_op=view_citation&hl=ru&user=5yBnCGoAAAAJ&citation_for_view=5yBnCGoAAAAJ:QIV2ME_5wuYC

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